Evolution of papillary thyroid cancer in acromegaly

Case series

Additional Files

Published

2021-08-19

How to Cite

Bautista Litardo, N., Salazar, P., Jaramillo Encalada, I., & Valdivieso Jara, S. (2021). Evolution of papillary thyroid cancer in acromegaly: Case series. Oncology Journal (Ecuador), 31(2), 131–140. https://doi.org/10.33821/560

Issue

Vol. 31 No. 2 (2021): August- November

Section

Original Articles

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Copyright (c) 2021 Noemí Bautista Litardo, Patricio Salazar, Ivanna Jaramillo Encalada, Sonia Valdivieso Jara

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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Authors

  • Noemí Bautista Litardo Endocrinology Service, National Oncological Institute “Dr. Juan Tanca Marengo ”SOLCA Guayaquil-Ecuador https://orcid.org/0000-0002-6321-970X
  • Patricio Salazar Endocrinology Service, "Teodoro Maldonado Carbo" Hospital, Ecuadorian Social Security Institute, Guayaquil-Ecuador
  • Ivanna Jaramillo Encalada Servicio de Endocrinología, Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón, Guayaquil-Ecuador
  • Sonia Valdivieso Jara Servicio de Endocrinología, Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón, Guayaquil-Ecuador

DOI:

https://doi.org/10.33821/560

Keywords:

Thyroid Cancer, Papillary, Thyroglobulin, Thyrotropin, Iodine Radioisotopes, Growth Hormone, Endothelial Growth Factors, Suppression, Growth Hormone

Abstract

Introduction: Acromegaly is produced by a somatotropic pituitary adenoma, which secretes an excessive production of GH and IGF1, it is related to a higher risk of malignant tumors, not being associated with a specific pattern of presentation and the objective of this study is to analyze the evolution of papillary thyroid cancer in acromegaly.

Cases report: These were three patients diagnosed with CPT with different prognosis, with facial characteristics, and symptoms such as headache, visual field alterations, menstrual alterations, which led to biochemical and imaging studies and the diagnosis of acromegaly.

Evolution:  The appearance of thyroid cancer in the time of evolution of acromegaly is different, in two of the cases it preceded it and in the third it was presented alongside this pathology. The response to treatment in CPT is indeterminate in the first patient and excellent in the other cases; remission was achieved in one patient.

Conclusions: It is concluded that the coexistence of acromegaly with thyroid cancer is possible, that the acral and facial changes and the expansive symptomatology of the tumor lead to the diagnosis of acromegaly and that the identification of malignancies is not related to the evolution of the disease.

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