Exercise in oncology: toward a fifth pillar of comprehensive cancer care
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Copyright (c) 2026 Mariana Vallejo Martínez
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
DOI:
https://doi.org/10.33821/883Abstract
After communicating a cancer diagnosis, the oncology team stages the disease and defines a therapeutic plan that may include surgery, radiotherapy, and systemic treatments such as chemotherapy, targeted therapies, and immunotherapy. However, structured exercise is still prescribed less frequently, despite existing evidence supporting its role in preserving functional capacity and reducing selected symptoms throughout the disease trajectory.
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Ligibel JA, Bohlke K, May AM, Clinton SK, Demark-Wahnefried W, Gilchrist SC, et al. Exercise, diet, and weight management during cancer treatment: ASCO guideline. J Clin Oncol. 2022;40(22):2491-2507. https://doi.org/10.1200/JCO.22.00687
Sanders JJ, Temin S, Ghoshal A, Alesi ER, Ali ZV, Chauhan C, et al. Palliative care for patients with cancer: ASCO guideline update. J Clin Oncol. 2024;42(19):2336-2357. https://doi.org/10.1200/JCO.24.00542
Campbell KL, Winters-Stone KM, Wiskemann J, May AM, Schwartz AL, Courneya KS, et al. Exercise guidelines for cancer survivors: Consensus statement from International Multidisciplinary Roundtable. Med Sci Sports Exerc. 2019;51(11):2375-2390. https://doi.org/10.1249/MSS.0000000000002116
Courneya KS, Vardy JL, O’Callaghan CJ, Gill S, Friedenreich CM, Wong RKS, et al. Structured exercise after adjuvant chemotherapy for colon cancer. N Engl J Med. 2025;393(1):13-25. https://doi.org/10.1056/NEJMoa2502760
Chan KKW, Chu RWK, Cheung MC, Courneya KS, O’Callaghan CJ, Vardy JL, et al. Structured exercise program after adjuvant chemotherapy for colon cancer: a cost-utility analysis of the CHALLENGE trial. J Clin Oncol. 2026;44(22):2130-2139. https://doi.org/10.1200/JCO-26-00765
Pentheroudakis G, Argilés G, Arnold D, Smyth E, Ducreux M. ESMO Clinical Practice Guideline Express Update on the adoption of physical exercise in patients with localised colon cancer. ESMO Open. 2026;11(2):106019. https://doi.org/10.1016/j.esmoop.2025.106019
Cao A, Ferrucci LM, Caan BJ, Irwin ML. Effect of exercise on sarcopenia among cancer survivors: A systematic review. Cancers (Basel). 2022;14(3):786. https://doi.org/10.3390/cancers14030786
Wang J, He Y, Kim AR, Lee KH, Choi SW. Effects of different types of exercise on inflammatory markers in cancer patients: a systematic review and Bayesian network meta-analysis. J Sports Sci. 2025;43(12):1121-1138. https://doi.org/10.1080/02640414.2025.2486886
